The Greatest Guide To indazole bioisostere
The Greatest Guide To indazole bioisostere
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Indazoles are a class of heterocyclic compounds which has a bicyclic ring structure made up of a pyrazole ring plus a benzene ring. Indazole-made up of compounds with various practical groups have crucial pharmacological pursuits and can be employed as structural motifs in designing novel drug molecules.
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11B) by introducing a fluorine group at distinct positions within the indazole ring. It is actually noted that the compound having fluorine at C7 (Fig. 11C) confirmed the highest hypotensive and bradycardic activities in in vivo
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